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Article

Mature dendritic cells are protected from Fas/CD95-mediated apoptosis by upregulation of Bcl-X(L).

Cancer immunology, immunotherapy : CII - 1 May 2002

Lundqvist Andreas, Nagata Takako, Kiessling Rolf, Pisa Pavel

Abstract excerpt

The clinical use of dendritic cells (DC) as tumor vaccines is very much dependent on their survival potential. Members of the tumor necrosis factor (TNF) receptor superfamily and their ligands are involved in the regulation of cell death. Fas (CD95) is a representative protein that promotes apoptosis. The Bcl-2 family of proteins functions as an integrator of diverse pro- and anti-apoptotic signals. It has been...

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Identifiers

PMID: 11941452
DOI: 10.1007/s00262-002-0265-7
PMCID: PMC11032821

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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