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Article

Apolipoprotein E and alpha-1-antichymotrypsin genotypes do not predict time to psychosis in Alzheimer's disease.

Journal of geriatric psychiatry and neurology - 1 Jan 2002

Sweet Robert A, Kamboh M Ilyas, Wisniewski Stephen R, Lopez Oscar L, Klunk William E, Kaufer Daniel I, DeKosky Steven T

Abstract excerpt

Psychotic symptoms occurring in Alzheimer's disease (AD + psychosis, AD + P) are a marker for a more rapidly deteriorating phenotype. We have developed a polygenic model of AD + P risk, conditioned on the presence of AD. Whether risk genes for AD itself contribute to AD + P risk is not established, although our model predicts they will not. The most important identified genetic determinant of sporadic, late-onset...

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PMID: 11936240
DOI: 10.1177/089198870201500106

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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