Article
Apolipoprotein epsilon4 advances appearance of psychosis in patients with Parkinson's disease.
Acta neurologica Scandinavica - 1 Jan 2006
Feldman B, Chapman J, Korczyn A D
Abstract excerpt
BACKGROUND: Psychosis is one of the most serious complications of advanced parkinsonism, but many patients are spared. The genetic factors predisposing to psychosis are unclear. OBJECTIVES: To assess the association between apolipoprotein E (APOE) polymorphism and the development of psychosis in patients with Parkinson's disease (PD). METHODS: Eighty-seven patients with advanced PD were assessed. Psychosis was...
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