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Article

Apolipoprotein epsilon4 advances appearance of psychosis in patients with Parkinson's disease.

Acta neurologica Scandinavica - 1 Jan 2006

Feldman B, Chapman J, Korczyn A D

Abstract excerpt

BACKGROUND: Psychosis is one of the most serious complications of advanced parkinsonism, but many patients are spared. The genetic factors predisposing to psychosis are unclear. OBJECTIVES: To assess the association between apolipoprotein E (APOE) polymorphism and the development of psychosis in patients with Parkinson's disease (PD). METHODS: Eighty-seven patients with advanced PD were assessed. Psychosis was...

Topics

Age of Onset
Apolipoprotein E4
Apolipoproteins E
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Parkinson Disease
Proportional Hazards Models
Psychotic Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Source

Identifiers

PMID: 16367893
DOI: 10.1111/j.1600-0404.2005.00535.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16367893-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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