Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation.

Development (Cambridge, England) - 1 Apr 2002

Damert Annette, Miquerol Lucile, Gertsenstein Marina, Risau Werner, Nagy Andras

Abstract excerpt

Vascular endothelial growth factor A (VEGFA) plays a pivotal role in the first steps of endothelial and haematopoietic development in the yolk sac, as well as in the establishment of the cardiovascular system of the embryo. At the onset of gastrulation, VEGFA is primarily expressed in the yolk sa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Endoderm
Share to Endothelial Growth Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Hematopoiesis

Share to Lac Operon

Share to Vascular Endothelial Growth Factor A

Share to Yolk Sac

Source

Identifiers

PMID: 11934854
DOI: 10.1242/dev.129.8.1881

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11934854-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation.PMID 11934854Read ↗

Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression.Semantic proximity Read ↗

Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant.Semantic proximity Read ↗

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene.Semantic proximity Read ↗

Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3Semantic proximity Read ↗

A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos.Semantic proximity Read ↗

Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures.Semantic proximity Read ↗

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele.Semantic proximity Read ↗

Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A.Semantic proximity Read ↗

Roles of VEGF-A signalling in development, regeneration, and tumoursSemantic proximity Read ↗

Angiopoietin-1 is essential in mouse vasculature during development and in response to injurySemantic proximity Read ↗

Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish.Semantic proximity Read ↗

Critical requirement of VEGF-C in transition to fetal erythropoiesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.