Article
The Candida albicans Sup35p protein (CaSup35p): function, prion-like behaviour and an associated polyglutamine length polymorphism.
Microbiology (Reading, England) - 1 Apr 2002
Resende Catarina, Parham Steven N, Tinsley Caroline, Ferreira Paulo, Duarte Júlio A B, Tuite Mick F
Abstract excerpt
The Sup35p protein of Saccharomyces cerevisiae is an essential translation factor whose prion-like properties give rise to the non-Mendelian genetic element [PSI(+)]. In this study the SUP35 gene from the related yeast species Candida albicans has been characterized. The CaSUP35 gene encodes a protein (CaSup35p) of 729 aa which shows 65% amino acid identity to the S. cerevisiae Sup35p protein (ScSup35p), with the...
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