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Article

Characterization of a bi-directional promoter for divergent transcription of a PHD-zinc finger protein gene and a ran gene in the protozoan pathogen Giardia lamblia.

Molecular microbiology - 1 Feb 2002

Ong Shiou-Jeng, Huang Li-Chin, Liu Hsing-Wei, Chang Shih-Chia, Yang Yen-Ching, Bessarab Irina, Tai Jung-Hsiang

Abstract excerpt

We showed previously that transcription of the ran gene in Giardia lamblia is regulated by an AT-rich initiator. In the present study, the ran initiator was found to regulate transcription of a neighbouring PHD zinc-finger protein gene. Deletion and scanning mutagenesis of the phd promoter in a firefly luciferase reporter system showed that the promoter activity is determined by multiple single-stranded T-tract...

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PMID: 11929523
DOI: 10.1046/j.1365-2958.2002.02772.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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