Article
Characterization of an iron-responsive promoter in the protozoan pathogen Trichomonas vaginalis.
The Journal of biological chemistry - 15 Feb 2002
Tsai Chu-Dang, Liu Hsing-Wei, Tai Jung-Hsiang
Abstract excerpt
Iron has been shown to regulate transcription in the protozoan pathogen Trichomonas vaginalis. In this study, a DNA transfection system was developed to monitor ap65-1 promoter activity in response to changing iron supply. In conjunction with electrophoretic mobility shift assay, iron-induced transcription of the ap65-1 gene was shown to be regulated by multiple closely spaced DNA elements spanning an...
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