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Article

Transcriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NFkappa B.

The Journal of biological chemistry - 14 Jun 2002

Cappellen David, Luong-Nguyen Ngoc-Hong, Bongiovanni Sandrine, Grenet Olivier, Wanke Christoph, Susa Mira

Abstract excerpt

Cytokines macrophage colony stimulating factor (M-CSF) and the receptor activator of NFkappaB ligand (RANKL) induce differentiation of bone marrow hematopoietic precursor cells into bone-resorbing osteoclasts without the requirement for stromal cells of mesenchymal origin. We used this recently described mouse cell system and oligonucleotide microarrays representing about 9,400 different genes to analyze gene...

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Source

Identifiers

PMID: 11923298
DOI: 10.1074/jbc.M200434200

Genes

IGF1
RIPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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