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Article

MITF and PU.1 Recruit p38 MAPK and NFATc1 to Target Genes during Osteoclast Differentiation

3 Apr 2007

Abstract excerpt

Transcription factors NFATc1, PU.1, and MITF collaborate to regulate specific genes in response to colony-stimulating factor-1 (CSF-1) and receptor activator of NF-kappaB ligand (RANKL) signaling during osteoclast differentiation. However, molecular details concerning timing and mechanism of specific events remain ill-defined. In bone marrow-derived precursors, CSF-1 alone promoted assembly of MITF-PU.1 complexes...

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PMID: 17403683
DOI: 10.1074/jbc.m609723200

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MITF and PU.1 Recruit p38 MAPK and NFATc1 to Target Genes during Osteoclast DifferentiationPMID 17403683Read ↗

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