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Article

Significance of the association between heparin‐binding epidermal growth factor‐like growth factor and CD9 in human gastric cancer

22 Jan 2002

Abstract excerpt

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family. Juxtacrine activity of proHB-EGF (the membrane-anchored form of HB-EGF) has been shown to be significantly potentiated when it is coexpressed with CD9 in vitro. The purpose of our study was to investigate the issue of whether proHB-EGF and CD9 are coexpressed in gastric cancer. HB-EGF gene expression and protein...

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PMID: 11920609
DOI: 10.1002/ijc.10198

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