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Article

The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies.

Journal of molecular biology - 15 Mar 2002

Visintin Michela, Settanni Giovanni, Maritan Amos, Graziosi Sergio, Marks James D, Cattaneo Antonino

Abstract excerpt

We describe the application of an intracellular antibody capture technology (IACT) as a generic in vivo selection procedure for isolating intracellular antibodies or ICAbs. IACT was applied to the de novo selection of functional ICAbs against the microtubule-associated protein TAU, found in neurofibrillary lesions of Alzheimer's disease brains. A panel of 17 different ICAbs was created which bind TAU inside cells...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11916379
DOI: 10.1006/jmbi.2002.5392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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