Article
Genotyping of Snps in a polyploid genome by pyrosequencing.
BioTechniques - 1 Mar 2002
Rickert Andreas M, Premstaller Andreas, Gebhardt Christiane, Oefner Peter J
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations, and they have become increasingly popular markers for association studies. Allelic discrimination of the mostly binary SNPs has been reported for diploid species, mainly the human, but not for polyploid genomes such as the agriculturally important crops. In the present study, we analyzed the applicability of pyrosequencing to...
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