Article
Endothelial signaling in kidney morphogenesis: a role for hemodynamic forces.
Current biology : CB - 19 Mar 2002
Serluca Fabrizio C, Drummond Iain A, Fishman Mark C
Abstract excerpt
The local presence of endothelial cells seems necessary for proper embryonic development of several organs. However, the signals involved are unknown. The glomerulus is generated by the coalescence of podocytes around an ingrowing capillary and is the site of blood ultrafiltration. In the absence of vessels, glomerular assembly does not occur. We describe mutations in the zebrafish that prevent glomerulogenesis....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.