Article
Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells.
Molecular biology of the cell - 1 Mar 2002
Alb James G, Phillips Scott E, Rostand Kathleen, Cui Xiaoxia, Pinxteren Jef, Cotlin Laura, Manning Timothy, Guo Shuling, York John D, Sontheimer Harald, Collawn James F, Bankaitis Vytas A
Abstract excerpt
Phosphatidylinositol transfer proteins (PITPs) regulate the interface between signal transduction, membrane-trafficking, and lipid metabolic pathways in eukaryotic cells. The best characterized mammalian PITPs are PITP alpha and PITP beta, two highly homologous proteins that are encoded by distinct genes. Insights into PITP alpha and PITP beta function in mammalian systems have been gleaned exclusively from...
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