Article
Recognition of the Measles Virus Nucleocapsid as a Mechanism of IRF-3 Activation
15 Apr 2002
Abstract excerpt
The mechanisms of cellular recognition for virus infection remain poorly understood despite the wealth of information regarding the signaling events and transcriptional responses that ensue. Host cells respond to viral infection through the activation of multiple signaling cascades, including the activation of NF-kappaB, c-Jun/ATF-2 (AP-1), and the interferon regulatory factors (IRFs). Although viral products...
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