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Fertilization in Vitro of Mouse Ova from Inbred and Outbred Strains: Complete Preimplantation Embryo Development in Glucose-Supplemented KSOM1

1 Aug 1995

Abstract excerpt

A new medium derived from the use of sequential simplex optimization methods (SOM) that overcomes the block to development beyond two cells in vitro in embryos of the CF1-cultured strain of mouse has recently been described. Contrary to previous reports, glucose was shown to have no significant inhibiting effect on embryo development to the blastocyst stage in SOM. A modification of SOM, designated KSOM, with an...

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PMID: 7492697
DOI: 10.1095/biolreprod53.2.431

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