Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular reactivity to angiotensin II alone or combined with a thromboxane A2 mimetic in the isolated perfused kidney of Lyon hypertensive rats.

Fundamental & clinical pharmacology - 1 Feb 2002

Oréa Valérie, Liu Kiao Ling, Benzoni Daniel

Abstract excerpt

The aim of this study was to evaluate whether thromboxane A2-prostaglandin H2 (TP) receptor activation potentiates the renal vasoconstrictor effect of Angiotensin II (Ang II) in genetically hypertensive rats of the Lyon strain (LH). Concentration-response curves (CRCs) to Ang II (5 pM to 10 nM), to the specific TP receptor agonist U46619 (7.5-960 nM) and to a mixture of Ang II + U46619 (fixed molar ratio of 1 :...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Drug Synergism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Vitro Techniques

Share to Perfusion

Share to Rats, Inbred Strains

Share to Receptors, Prostaglandin

Share to Vascular Resistance

Share to Vasoconstrictor Agents

Source

Identifiers

PMID: 11903507
DOI: 10.1046/j.1472-8206.2002.00067.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Vascular reactivity to angiotensin II alone or combined with a thromboxane A2 mimetic in the isolated perfused kidney of Lyon hypertensive rats.PMID 11903507Read ↗

Increased renal vascular sensitivity to angiotensin II in hypertension is due to decreased response to prostaglandins.Semantic proximity Read ↗

Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP.Semantic proximity Read ↗

Comparison Of Cardiovascular Characteristics In Normotensive And Hypertensive Rat Strains.Semantic proximity Read ↗

Vascular contractile reactivity in hypotension due to reduced renal reabsorption of Na+ and restricted dietary Na.Semantic proximity Read ↗

Hemodynamic phenotyping of transgenic rats with ubiquitous expression of an angiotensin-(1-7)-producing fusion protein.Semantic proximity Read ↗

Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics.Semantic proximity Read ↗

Effect of early blockade of bradykinin B2-receptors on the blood pressure phenotype of normotensive and spontaneously hypertensive rats.Semantic proximity Read ↗

Altered regulation of endothelin A receptor subtype in the cerebral arterioles in response to a Japanese-style diet, in stroke-prone hypertensive rats.Semantic proximity Read ↗

Early blockade of bradykinin B2-receptors alters the adult cardiovascular phenotype in rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.