Article
[Characterization of the expression and function of SigM an ECF sigma factor in mycobacteria].
Acta cientifica venezolana - 1 Jan 2001
Arráiz N, Salazar L, López G, Rodríguez R, Casart Y, Takiff H
Abstract excerpt
The survival of M. tuberculosis within the macrophage depends on its ability to respond to oxidative stress, and the ECF subfamily of sigma factors likely play an important role. We studied SigM, a sigma factor whose gene is located near the origin of DNA replication. In both M. smegmatis and M. bovis BCG, the expression of sigM was induced at high temperature and in stationary phase. Mutants of M. smegmatis...
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