Article
The Human ATP-Binding Cassette Transporter Genes From the Bench to the Bedside
1 Mar 2001
Abstract excerpt
ATP-binding cassette (ABC) transporter genes are ubiquitously present in most organisms from bacteria to man. This gene family is the largest one known as of yet. Still growing, the number of human ABC transporters counts currently 47 members which belong to seven subfamilies. ABC transporters share a similar molecular architecture (1) Full-structured transporters harbor two symmetric halves each consisting of...
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