Article
Heritability of longitudinal change in lung function. The Framingham study.
American journal of respiratory and critical care medicine - 1 Nov 2001
Gottlieb D J, Wilk J B, Harmon M, Evans J C, Joost O, Levy D, O'Connor G T, Myers R H
Abstract excerpt
There have been multiple reports of heritability of lung function in cross-sectional analysis, but no prior reports of heritability of rate of change in lung function. We examined heritability of rate of change of lung function in families participating in the Framingham Heart Study. Spirometric measures from two time points were used to calculate annualized rate of change in FEV(1), FVC, and FEV(1)/FVC ratio,...
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