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Article

Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors.

The Journal of comparative neurology - 18 Mar 2002

Hanbury Rose, Charles Vinod, Chen Er-Yun, Leventhal Liza, Rosenstein Jeffrey M, Mufson Elliott J, Kordower Jeffrey H

Abstract excerpt

After injury, the striatum displays several morphologic responses that may play a role in both regenerative and degenerative events. One such response is the de novo expression of the low-affinity p75 neurotrophin receptor (p75(NTR)), a gene that plays critical roles in central nervous system (CNS) cell death pathways. The present series of experiments sought to elucidate the cellular origins of this p75(NTR)...

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PMID: 11891644
DOI: 10.1002/cne.10104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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