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Article

Conflicting levels of selection in the accumulation of mitochondrial defects in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Taylor Douglas R, Zeyl Clifford, Cooke Erin

Abstract excerpt

The somatic accumulation of defective mitochondria causes human degenerative syndromes, senescence in fungi, and male sterility in plants. These diverse phenomena may result from conflicts between natural selection at different levels of organization. Such conflicts are fundamental to the evolution of cooperating groups, from cells to populations. We present a model in which defective mitochondrial genomes...

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Identifiers

PMID: 11891344
DOI: 10.1073/pnas.072660299
PMCID: PMC122585

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Source receipt: pubmed, retrieved 7 Sept 2026.

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