Article
A large gene family for putative variant antigens shared by human and rodent malaria parasites.
Proceedings. Biological sciences - 22 Feb 2002
Janssen Christoph S, Barrett Michael P, Turner C Michael R, Phillips R Stephen
Abstract excerpt
A major mechanism whereby malaria parasites evade the host immune response to give chronic infections in patients' blood for months, or even years, is antigenic variation. In order to generate variant antigens, parasites require large multigene families. Although several gene families involved in these phenomena have been identified in the human malaria Plasmodium falciparum, to date no variant antigen gene...
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