Article
The varieties of gene amplification, diversification and hypervariability in the human malaria parasite, Plasmodium falciparum.
Molecular and biochemical parasitology - 1 Aug 2009
Templeton Thomas J
Abstract excerpt
The human malaria parasite, Plasmodium falciparum, is able to evade host cell-mediated and humoral immunity to maintain both persistent and repeated infections. Immune evasion is in part due to a robust repertoire of proteins which participate in host-parasite interactions but also exhibit profound antigenic diversity, and in some instances switches in gene expression. The antigenic diversity occurs both at the...
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