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Article

Host immunity modulates transcriptional changes in a multigene family (yir) of rodent malaria

22 Sept 2005

Abstract excerpt

Variant antigens, encoded by multigene families, and expressed at the surface of erythrocytes infected with the human malaria parasite Plasmodium falciparum and the simian parasite Plasmodium knowlesi, are important in evasion of host immunity. The vir multigene family, encoding a very large number of variant antigens, has been identified in the human parasite Plasmodium vivax and homologues (yir) of this family...

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PMID: 16238615
DOI: 10.1111/j.1365-2958.2005.04840.x

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