Article
Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis.
British journal of haematology - 1 Mar 2002
Rosendaal F R, Vessey M, Rumley A, Daly E, Woodward M, Helmerhorst F M, Lowe G D O
Abstract excerpt
Hormone replacement therapy (HRT) increases the risk of venous thrombosis. We investigated whether this risk is affected by carriership of hereditary prothrombotic abnormalities. Therefore, we determined the two most common prothrombotic mutations, factor V Leiden and prothrombin 20210A in women who participated in a case-control study on venous thrombosis. Relative risks were expressed as odds ratios (OR) with...
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