Article
Hypertension genetics, single nucleotide polymorphisms, and the common disease:common variant hypothesis.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2002
Doris Peter A
Abstract excerpt
The investigation of heritable susceptibility to disease is an effort to associate disease phenotype with underlying genotype. Such genotype:phenotype associations have been demonstrated for a large number of monogenetic disorders. The usual strategy has been to use linkage mapping in affected families to identify chromosomal loci from which candidate genes and genotypes can be tested for association with...
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