Article
Blood pressure and human genetic variation in the general population.
Current opinion in cardiology - 1 May 2010
Arora Pankaj, Newton-Cheh Christopher
Abstract excerpt
PURPOSE OF REVIEW: Hypertension is a complex trait with multiple environmental and genetic contributors. Until recently, linkage studies of rare Mendelian disorders of hypertension and hypotension have produced the most notable progress toward understanding the heritable basis of blood pressure (BP). Association studies to identify common variants have been limited in the past by small sample sizes and most...
Topics
- Blood Pressure
- Genetic Predisposition to Disease
- Genetic Variation
- Genome-Wide Association Study
- Humans
- Hypertension
- Mutation