Article
Use of single nucleotide polymorphisms for gene discovery in hypertension.
Current hypertension reports - 1 Feb 2000
Fornage M, Doris P A
Abstract excerpt
Genetic susceptibility to common diseases is likely influenced by common DNA variants with small-to-moderate effects, rather than by rare mutations with large effects. The majority of such common variation occurs in the form of single nucleotide polymorphisms (SNPs). DNA sequence variation, including SNPs, is created and maintained by the action of evolutionary forces such as mutation, recombination, and...
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