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Article

Neoplastic Transformation of Human Small Airway Epithelial Cells Induced by Arsenic

1 Jan 2008

Abstract excerpt

Human small airway epithelial cells (SAECs) previously immortalized with human telomerase reverse transcriptase (h-TERT) were continuously treated with sodium arsenite at a dose of 0.5 microg/mL in culture for up to 6 months. Arsenic-treated cells progressively displayed an increase in transformed phenotype including enhanced growth saturation density, plating efficiency, and anchorage-independent growth and...

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PMID: 18037969
DOI: 10.2119/2007-00090.wen

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