Article
Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.
Pharmacogenomics - 1 Oct 2004
Solus Joseph F, Arietta Brenda J, Harris James R, Sexton David P, Steward John Q, McMunn Chara, Ihrie Patrick, Mehall Janelle M, Edwards Todd L, Dawson Elliott P
Abstract excerpt
The extent of genetic variation found in drug metabolism genes and its contribution to interindividual variation in response to medication remains incompletely understood. To better determine the identity and frequency of variation in 11 phase I drug metabolism genes, the exons and flanking intronic regions of the cytochrome P450 (CYP) isoenzyme genes CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19,...
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