Article
G protein beta 3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE Family Study.
Physiological genomics - 28 Feb 2002
Rankinen Tuomo, Rice Treva, Leon Arthur S, Skinner James S, Wilmore Jack H, Rao D C, Bouchard Claude
Abstract excerpt
A C825T polymorphism of the G protein beta3 (GNB3) gene has been reported to be associated with hypertension and obesity. We analyzed the associations between the GNB3 C825T polymorphism and hemodynamic and body composition phenotypes in the sedentary state and their responses to endurance training in mainly normotensive white (n = 473) and black (n = 255) men and women. Blood pressure (BP) and heart rate (HR)...
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