Article
Association of GNB3 C825T polymorphism with peak oxygen consumption.
International journal of sports medicine - 1 May 2009
Faruque M U, Millis R M, Dunston G M, Kwagyan J, Bond V, Rotimi C N, Davis T, Christie R, Campbell A L
Abstract excerpt
The C825T single nucleotide polymorphism (SNP) in the guanine nucleotide-binding protein, beta polypeptide 3 ( GNB3) gene gives rise to a splice variant, GNB3s that has enhanced G protein activation and signal transduction activity. This variant has been reported to be associated with cardiovascular disease, diabetes and obesity. We studied this SNP in 95 healthy 18 to 30 year-old African American university...
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