Article
c-erbB-2 is not a major factor in the development of colorectal cancer.
British journal of cancer - 12 Feb 2002
McKay J A, Loane J F, Ross V G, Ameyaw M-M, Murray G I, Cassidy J, McLeod H L
Abstract excerpt
We have investigated c-erbB-2 protein expression in a large cohort of well-characterized colorectal tumours, and in a subset of lymph node metastases. We have also evaluated a Val(655)Ile single nucleotide polymorphism, which is associated with an increased risk of breast cancer, in a subset of the colorectal cancer patients and in healthy control subjects. Immunohistochemical studies revealed that while 81.8% of...
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