Article
No association between HER-2 gene polymorphism at codon 655 and a risk of bladder cancer.
International journal of cancer - 20 Feb 2002
Wang Lizhong, Habuchi Tomonori, Takahashi Takeshi, Kamoto Toshiyuki, Zuo Tao, Mitsumori Kenji, Tsuchiya Norihiko, Sato Kazunari, Ogawa Osamu, Kato Tetsuro
Abstract excerpt
The amplification and overexpression of the human epidermal growth factor receptor 2 gene HER-2 (also known as c-erb-B2 or neu) have been shown to be associated with bladder cancer and its progression. Recent studies indicated an association between the Ile to Val polymorphism at codon 655 of HER-2 and susceptibility to breast cancer. To investigate the correlation between the Ile/Val polymorphism and the...
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