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Article

Sp1 and Egr1 Regulate Transcription of the Dmrt1 Gene in Sertoli Cells1

1 Mar 2002

Abstract excerpt

Dmrt1 is a recently described gene that is specifically expressed in the gonads and is required for postnatal testis differentiation. Here, we describe the transcriptional mechanisms regulating the Dmrt1 proximal promoter in testicular Sertoli cells. A genomic clone containing exon 1 of the rat Dmrt1 gene and more than 9 kilobases of 5' flanking sequence was isolated and characterized. Several prominent...

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PMID: 11870074
DOI: 10.1095/biolreprod66.3.675

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