Article
Identification, characterization, and functional analysis of sp1 transcript variants expressed in germ cells during mouse spermatogenesis.
Biology of reproduction - 1 Apr 2005
Thomas Kelwyn, Sung Dae-Yong, Yang Jun, Johnson Kwame, Thompson Winston, Millette Clarke, McCarrey John, Breitberg Andrew, Gibbs Robert, Walker William
Abstract excerpt
The SP family of zinc-finger transcription factors are important mediators of selective gene activation during embryonic development and cellular differentiation. SP-binding GC-box domains are common cis-regulatory elements present in the promoters of several genes expressed in a developmentally specific manner in differentiating mouse germ cells. Four Sp1 cDNAs were isolated from a mouse pachytene spermatocyte...
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