Article
TOC-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant Staphylococcus aureus.
Antimicrobial agents and chemotherapy - 1 May 1995
Hanaki H, Akagi H, Masaru Y, Otani T, Hyodo A, Hiramatsu K
Abstract excerpt
TOC-39, a new parenteral cephalosporin, is a hydroxyimino-type cephem antibiotic with vinylthio-pyridyl moiety at the 3 position. TOC-39 was evaluated for antibacterial activity against various clinically isolated strains. TOC-39 had excellent activity, stronger than that of methicillin, oxacilli...
Topics
- Animals
- Bacteria
- Cephalosporins
- Escherichia coli Infections
- Male
- Methicillin Resistance
- Mice
- Mice, Inbred Strains
- Microbial Sensitivity Tests
- Mutation
- Staphylococcal Infections
- Staphylococcus aureus