Article
Genotypes of the betaENaC gene have little influence on blood pressure level in the Japanese population.
American journal of hypertension - 1 Feb 2002
Matsubara Mitsunobu, Metoki Hirohito, Suzuki Michiko, Fujiwara Tohru, Kikuya Masahiro, Michimata Mari, Ohkubo Takayoshi, Hozawa Atsushi, Tsuji Ichiro, Hisamichi Shigeru, Araki Tsutomu, Imai Yutaka
Abstract excerpt
The gene for the beta-subunit of the epithelial sodium channel (betaENaC) is one of the most prominent candidate genes being analyzed for an association with human essential hypertension. It is known that a deletion or alteration of PY motif in exon 12 of betaENaC is responsible for Liddle's syndrome. Although the localization of genetic polymorphisms of betaENaC is unique to each population, intensive analysis...
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