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Article

Lack of association of functional variants in alpha-ENaC gene and essential hypertension in two ethnic groups in China.

Kidney & blood pressure research - 1 Jan 2008

Wang Xiao-feng, Lu Xiao-mei, Lin Ren-yong, Wang Shi-zhen, Zhang Li-ping, Qian Ji, Lu Da-ru, Wen Hao, Jin Li

Abstract excerpt

BACKGROUND: It has been proposed that subtle genetic changes in epithelial sodium channel (ENaC) subunits might be at the origin of less rare forms of hypertension. In some populations, subtle functional genetic changes in ENaC genes associated with essential hypertension were indeed observed. To further test this hypothesis, we observed the role of three functional variants G2139A, A334T and A663T in the...

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Identifiers

PMID: 18703878
DOI: 10.1159/000151286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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