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Article

Genetic analysis of the beta subunit of the epithelial Na+ channel in essential hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Jul 1998

Persu A, Barbry P, Bassilana F, Houot A M, Mengual R, Lazdunski M, Corvol P, Jeunemaitre X

Abstract excerpt

Mutations of the last exon of the beta subunit of the amiloride-sensitive epithelial Na+ channel (betaENaC) can lead to Liddle's syndrome, a rare monogenic form of hypertension. The objective of this study was to test whether more subtle changes of betaENaC could be implicated in essential hypertension. After determination of the betaENaC coding gene organization (12 exons spanning 23.5 kb), a systematic...

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Identifiers

PMID: 9674649
DOI: 10.1161/01.hyp.32.1.129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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