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Article

Patterns of genetic variation at a chromosome 4 locus of Drosophila melanogaster and D. simulans.

Genetics - 1 Feb 2002

Jensen Mark A, Charlesworth Brian, Kreitman Martin

Abstract excerpt

DNA sequence surveys of Drosophila melanogaster populations show a strong positive correlation between the recombination rate experienced by a locus and its level of nucleotide polymorphism. In particular, surveys of the fourth chromosome gene ci(D) show greatly reduced levels of nucleotide variation; this observation was originally interpreted in terms of selective sweeps occurring on the nonrecombining fourth...

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Identifiers

PMID: 11861556
DOI: 10.1093/genetics/160.2.493
PMCID: PMC1461959

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