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Article

Nucleotide variation along the Drosophila melanogaster fourth chromosome.

Science (New York, N.Y.) - 4 Jan 2002

Wang Wen, Thornton Kevin, Berry Andrew, Long Manyuan

Abstract excerpt

The Drosophila melanogaster fourth chromosome, believed to be nonrecombining and invariable, is a classic example of the effect of natural selection in eliminating genetic variation in linked loci. However, in a chromosome-wide assay of nucleotide variation in natural populations, we have observed a high level of polymorphism in a approximately 200-kilobase region and marked levels of polymorphism in several...

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PMID: 11778050
DOI: 10.1126/science.1064521

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