Article
A genome-wide departure from the standard neutral model in natural populations of Drosophila.
Genetics - 1 Sept 2000
Andolfatto P, Przeworski M
Abstract excerpt
We analyze nucleotide polymorphism data for a large number of loci in areas of normal to high recombination in Drosophila melanogaster and D. simulans (24 and 16 loci, respectively). We find a genome-wide, systematic departure from the neutral expectation for a panmictic population at equilibrium in natural populations of both species. The distribution of sequence-based estimates of 2Nc across loci is...
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