Article
Biochip-based detection of KRAS mutation in non-small cell lung cancer.
International journal of molecular sciences - 1 Jan 2011
Kriegshäuser Gernot, Fabjani Gerhild, Ziegler Barbara, Zöchbauer-Müller Sabine, End Adelheid, Zeillinger Robert
Abstract excerpt
This study is aimed at evaluating the potential of a biochip assay to sensitively detect KRAS mutation in DNA from non-small cell lung cancer (NSCLC) tissue samples. The assay covers 10 mutations in codons 12 and 13 of the KRAS gene, and is based on mutant-enriched PCR followed by reverse-hybridi...
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