Article
Usefulness of automated chromatography for rapid fetal blood analysis for second trimester prenatal diagnosis of beta-thalassemia.
Prenatal diagnosis - 1 Feb 2002
Wadia Mahrukh R, Phanasgaokar Supriya P, Nadkarni Anita H, Surve Reema R, Gorakshakar Ajit C, Colah Roshan B, Mohanty Dipika
Abstract excerpt
Prenatal diagnosis of beta-thalassemia is now ideally done in the first trimester of pregnancy by chorionic villus tissue DNA analysis. Nevertheless, fetal blood analysis in the second trimester is required either when the mutation in both parents cannot be characterised or when the couple comes late for investigations. We evaluated the usefulness of analysis of fetal blood on the Biorad Variant Hemoglobin...
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