Article
Prenatal diagnosis of beta-thalassemia major by high-performance liquid chromatography analysis of hemoglobins in fetal blood samples.
Hemoglobin - 1 Feb 2001
Sanguansermsri T, Thanarattanakorn P, Steger H F, Tongsong T, Chanprapaph P, Wanpirak C, Siriwatanapa P, Sirichotiyakul S, Flatz G
Abstract excerpt
In Thailand and adjacent countries, most of the beta-thalassemia genes are beta(0)-thalassemia mutations that prevent the production of Hb A. We propose the quantitation of the Hb A fraction in fetal blood in the mid-trimester of pregnancy by automated high performance liquid chromatography as a reasonable prenatal diagnostic method to be applied in areas with limited laboratory facilities. Forty pregnant women...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.