Article
Newborn screening for haemoglobinopathies by high performance liquid chromatography (HPLC): diagnostic utility of different approaches in resource-poor settings.
Clinical chemistry and laboratory medicine - 1 Dec 2014
Upadhye Dipti S, Jain Dipty L, Trivedi Yogesh L, Nadkarni Anita H, Ghosh Kanjaksha, Colah Roshan B
Abstract excerpt
BACKGROUND: Sickle cell disease is a major health burden in India. The aim of the study was to compare the diagnostic utility of two different approaches on automated high performance liquid chromatography (HPLC) for newborn screening for sickle cell disorders and other haemoglobinopathies in India. METHODS: Newborn babies of sickle heterozygous mothers were tested by HPLC using two different kits, the β-thal...
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