Article
Evaluation of an automated capillary electrophoresis system in the screening for hemoglobinopathies.
Clinical laboratory - 1 Jan 2009
Cotton Frederic, Malaviolle Xavier, Vertongen Françoise, Gulbis Béatrice
Abstract excerpt
BACKGROUND: The biochemical diagnosis of hemoglobinopathies (thalassemias and hemoglobin (Hb) variants) is based on the separation and the quantification of Hb fractions. HPLC is the most commonly used method but capillary electrophoresis (CE) methods have also been developed successfully. The Capillarys II system is the first fully automated CE system that allows the quantification of Hb A2 and Hb F and the...
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