Article
Serotonin transporter gene polymorphisms in alcohol dependence.
Alcohol (Fayetteville, N.Y.) - 1 Oct 2000
Thompson M D, Gonzalez N, Nguyen T, Comings D E, George S R, O'Dowd B F
Abstract excerpt
The serotonin transporter (5-HTT) gene is a candidate gene in alcohol dependence because serotonin reuptake inhibitors (SRIs) can alleviate alcohol withdrawal. Studies of the 5-HTT gene in alcohol dependence have not resulted in a consensus. Recent studies have examined the transcriptionally active promoter polymorphism, a 44-bp deletion resulting in short (S) or long (L) alleles. In this study, 131...
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